Khoom Description
Snap 8 peptide hmoovyog ib qho hluavtaws los tiv thaiv -aging peptide feem ntau tsim los txo cov tsos ntawm lub ntsej muag kab thiab wrinkles. Nws cov txheej txheem ntawm kev ua raws li N- ntu ntu ntawm SNAP-25 cov protein, maj mam cuam tshuam nrog kev tso tawm cov tshuaj neurotransmitters, yog li ua rau cov leeg tsis muaj zog thiab ua rau cov kab lus ntiav thiab luv, tshwj xeeb tshaj yog siv tau rau thaj chaw xws li hauv pliaj thiab ib ncig ntawm lub qhov muag. Raws li ib qho kev hloov kho dua tshiab ntawm cov tshuaj tiv thaiv ntau tshaj -wrinkle ingredient acetyl hexapeptide-3 (argirelin), SNAP-8 muaj ob qho amino acids ntxiv ntawm nws cov peptide saw, uas ua rau cov nyhuv softer thiab ntev ntev. Nws feem ntau yog ntxiv ntawm 3% -10% rau cov khoom siv tu tawv nqaij xws li cov tshuaj pleev, tshuaj pleev, gels, lossis lub ntsej muag.
Cov txiaj ntsig tseem ceeb ntawm Snap-8
1. Ua kom cov kab lus sib luag zoo
- Txo dynamic wrinkles tshwm sim los ntawm kev coj cwj pwm (xws li frowning thiab luag ntxhi) los ntawm kev so ntawm lub ntsej muag cov leeg.
- Tshwj xeeb tshaj yog zoo rau crow's ko taw, hauv pliaj wrinkles, thiab frown kab.
2. Yooj yim thiab nyab xeeb dua
- Tsis tas yuav txhaj tshuaj, tsis yog - daim ntawv thov ntxeem tau, tsis muaj zog zoo li Botox.
- Tsis tshua muaj khaus, haum rau kev tu tawv nqaij txhua hnub, thiab tuaj yeem siv rau thaj chaw rhiab xws li qhov muag qhov muag.
3. Cov txiaj ntsig zoo tshaj rau Classic Hexapeptides
- Snap 8 peptide hmoov yog ib qho kev hloov kho tshiab ntawm Argireline (acetyl hexapeptide-3).
- Cov ntaub ntawv kho mob qhia tau hais tias: qhov tob tob zuj zus los ntawm kwv yees li 35% hauv 28 hnub, ze li 30% zoo dua hexapeptides.
4. Precise Mechanism of Action
- High affinity lub hom phiaj tshwj xeeb proteins (dissociation tas li kwv yees li 0.8 μM).
- Cov qauv molecular ruaj khov ua kom ntev - ua haujlwm tau zoo hauv cov khoom.
5. Yooj yim rau siv thiab sib xws heev
- Tsis muaj daim ntawv thov kev tshaj lij; tuaj yeem muab tso ncaj qha rau hauv cov qauv niaj hnub xws li cov tshuaj pleev xim, tshuaj pleev, thiab tshuaj pleev qhov muag.
- Muaj peev xwm ua kom muaj txiaj ntsig zoo nrog rau lwm cov tshuaj tiv thaiv kev laus - cov khoom xyaw (xws li Matrixyl, retinol, thiab hyaluronic acid).
Kev Tswj Xyuas Zoo
1.Physicochemical Properties & Impurity Control
| Cov khoom kuaj | Quality Control Specification (Piv txwv) | Lub Hom Phiaj & Kev piav qhia |
|---|---|---|
| Qhov tshwm sim | Dawb hmoov | Xyuas seb daim ntawv lub cev thiab xim raws li qhov yuav tsum tau ua |
| tsw | Cov yam ntxwv tsw | Txiav txim siab seb puas muaj tawm - ntxhiab tsw lossis cov kuab tshuaj residues |
| Saj | Yam ntxwv saj | Qee COA suav nrog cov khoom kuaj no |
| Assay (Cov ntsiab lus) | Ntau dua lossis sib npaug li 98.0% lossis Ntau dua lossis sib npaug li 99.0% | Ncaj nraim ntsuas cov ntsiab lus meej ntawm cov khoom muaj txiaj ntsig, qhov txawv ntawm "purity" (uas yog qhov tshwm sim ntawm qhov chaw siab tshaj plaws) |
| Poob rau ziab | Tsawg dua lossis sib npaug li 5.0% | Tswj cov dej noo kom ntseeg tau tias hmoov ruaj khov thiab tiv thaiv clumping |
| Sulfated tshauv | Tsawg dua lossis sib npaug li 5.0% | Tshawb xyuas tag nrho cov seem ntawm inorganic impurities (xws li hlau ntsev) |
| Sieve Analysis | 100% dhau los ntawm 80 mesh | Xyuas cov hmoov fineness los xyuas kom meej solubility thiab daim tawv nqaij xav nyob rau hauv formulations |
| Total Heavy Metals | Tsawg dua lossis sib npaug li 10 ppm lossis 5 ppm | Tswj cov seem ntawm cov hlau hnyav xws li txhuas thiab mercury |
| Arsenic | Tsawg dua lossis sib npaug li 2 ppm | Tshawb xyuas cov teeb meem tshwj xeeb |
| Residual Solvents | Ua raws (tsis zoo lossis tsawg dua lossis sib npaug rau 0.05%) | Xyuas kom cov kuab tshuaj organic siv hauv kev sib txuas (xws li, ethanol) raug tshem tawm zoo |
2. Kev kuaj kab mob microbial
| Cov khoom kuaj | Quality Control Specification (Piv txwv) | Lub Hom Phiaj & Kev piav qhia |
|---|---|---|
| Tag Nrho Phaj suav | Tsawg dua lossis sib npaug li 100 CFU / g | Tshawb xyuas tag nrho aerobic microbial suav |
| Poov & Pwm | Tsawg dua lossis sib npaug li 10 CFU / g lossis Tsawg dua lossis sib npaug rau 100 CFU / g | Tshawb xyuas cov kab mob fungal |
| E. coli | Tsis Pom | Tshawb xyuas cov kab mob qhia rau cov kab mob fecal |
| Salmonellasp. | Tsis Pom | Tshawb xyuas cov kab mob pathogenic |
| S. aureus | Tsis Pom | Tshawb xyuas cov kab mob pathogenic (kuaj los ntawm qee cov tuam ntxhab) |
Txheej txheem ntau lawm
- Khoom -theem synthesis:Thawj cov amino acid yog immobilized ntawm resin, thiab cov amino acids tom ntej yog txuas mus ntxiv.
- Cleavage thiab tshem tawm:Synthesized peptide saw yog cleaved los ntawm cov cob.
- Purification:Cov impurities raug tshem tawm siv siab -kev ua haujlwm kua chromatography (HPLC).
- Lyophilization:Cov tshuaj purified yog lyophilized kom tau cov hmoov dawb.
- Zoo tswj thiab ntim:Purity, molecular hnyav, thiab lwm yam ntsuas tau raug kuaj. Tom qab dhau qhov kev ntsuam xyuas, cov hmoov tau ntim thiab khaws cia rau hauv qis - kub, lub teeb - tiv thaiv tej yam kev mob.
R & D Muaj peev xwm
Snap 8 peptide hmoovyog ib qho tshuaj tiv thaiv zoo heev -wrinkle ingredient siv nyob rau hauv cov khoom tu tawv nqaij, qhov tseem ceeb yog ib qho kev hloov kho tshiab ntawm classic anti-wrinkle ingredient "Argirelin." Nws cov kev tshawb fawb thiab kev loj hlob muaj peev xwm yog feem ntau cuam tshuam hauv cov hauv qab no:
1. Molecular Design
Cov kws tshawb fawb tau tshawb pom tias cov kab qhia tau tshwm sim los ntawm kev rov ua dua ntawm cov leeg ntawm lub ntsej muag. SNAP-8 tus qauv tsim lub tswv yim yog kom me ntsis "so" cov leeg, yog li txo qis wrinkles.
Piv nrog rau tiam dhau los ntawm cov khoom hexapeptide, SNAP-8 muaj ob qho amino acids ntxiv, thiab nws cov molecules tau raug hloov kho tshwj xeeb ntawm ob qho kawg, ua rau nws ruaj khov thiab nws cov teebmeem ntau meej.
2. Kev Tshawb Fawb Txog Kev Ua Haujlwm
Los ntawm kev txheeb xyuas dual hauv chav kuaj thiab tiag -kev sim neeg, qhov ua tau zoo ntawm SNAP-8 tau txais kev txhawb nqa los ntawm cov ntaub ntawv:
- 28-hnub sim tus neeg tiag tiag:Forehead wrinkle qhov tob txo los ntawm qhov nruab nrab ntawm kwv yees li 35%, nrog rau qhov siab tshaj plaws ntawm 63%.
- Piv rau tiam dhau los:Cov nyhuv yog kwv yees li 29% zoo dua li Argirelin.
- Mechanism ntawm kev ua:Txo cov leeg nqaij contraction signals los ntawm 63% thiab ncua cov teeb liab kis los ntawm 175%.
Nyob rau hauv luv luv, wrinkles yog noticeably ntiav, thiab cov nyhuv yog zoo dua ua ntej.
3.Production Process thiab Formulation
- Kev tsim tawm:Siv cov khoom ua kom paub tab-thev synthesis thev naus laus zis, kev tsim khoom tuaj yeem nce los ntawm me me -batch Laboratory ua hauj lwm mus rau loj -scale Hoobkas ntau lawm. Txhua batch ntawm cov khoom muaj ib daim ntawv ntsuam xyuas zoo.
- Cov lus pom zoo siv:Pom zoo qib ntxiv: 0.05% -0.5%. Feem ntau ruaj khov ntawm pH 5-6. Kev npaj kub yuav tsum tsis txhob siab tshaj 40 degree.
- Txiav -Kev Tshawb Fawb Ntug:Yuav tau encapsulated nrog nanocarriers los pab nyob rau hauv zoo dua daim tawv nqaij nqus.
Cim npe nrov: Tuam Tshoj snap 8 peptide hmoov manufacturers, lwm tus neeg, Hoobkas
